Scientific Name: Mesocricetus auratus
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Cricetidae
Summary: The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020] [NCBI] [Proteinatlas]
Data set information
Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
---|---|---|---|---|---|---|
Vthunter_0014 | 2021.04 | 10X Genomics | Frontal | Normal | 3269 | Link |
Vthunter_0015 | 2021.04 | 10X Genomics | Heart | Normal | 3063 | Link |
Vthunter_0016 | 2021.04 | 10X Genomics | Kidney | Normal | 7180 | Link |
Vthunter_0017 | 2021.04 | 10X Genomics | Liver | Normal | 18383 | Link |
Vthunter_0018 | 2021.04 | 10X Genomics | Lung | Normal | 1695 | Link |
Vthunter_110072 | 2019.12 | MARS-seq | TotalBrain | Normal | 768 | Link |
Featureplot of receptors
Expression: Biased expression in small intestine (RPKM 70.7), placenta (RPKM 57.1) and 13 other tissues